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Unravelling the Mechanistic Role of Quinazolinone Pharmacophore in the Inhibitory Activity of Bis-quinazolinone Derivative on Tankyrase-1 in the Treatment of Colorectal Cancer (CRC) and Non-small Cell Lung Cancer (NSCLC): A Computational Approach.
Okunlola, Felix O; Akawa, Oluwole B; Subair, Temitayo I; Omolabi, Kehinde F; Soliman, Mahmoud E S.
Afiliación
  • Okunlola FO; Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4001, South Africa.
  • Akawa OB; Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4001, South Africa.
  • Subair TI; Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4001, South Africa.
  • Omolabi KF; Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4001, South Africa.
  • Soliman MES; Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4001, South Africa. soliman@ukzn.ac.za.
Cell Biochem Biophys ; 80(1): 1-10, 2022 Mar.
Article en En | MEDLINE | ID: mdl-34453681
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Carcinoma de Pulmón de Células no Pequeñas / Tanquirasas / Inhibidores Enzimáticos / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Cell Biochem Biophys Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Sudáfrica
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Carcinoma de Pulmón de Células no Pequeñas / Tanquirasas / Inhibidores Enzimáticos / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Cell Biochem Biophys Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Sudáfrica