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How to get away with liver innate immunity? A viruses' tale.
Delphin, Marion; Desmares, Manon; Schuehle, Svenja; Heikenwalder, Mathias; Durantel, David; Faure-Dupuy, Suzanne.
Afiliación
  • Delphin M; International Center for Infectiology Research (CIRI), INSERM U1111, CNRS UMR5308, Université de Lyon (UCBL1), Lyon, France.
  • Desmares M; International Center for Infectiology Research (CIRI), INSERM U1111, CNRS UMR5308, Université de Lyon (UCBL1), Lyon, France.
  • Schuehle S; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Heikenwalder M; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
  • Durantel D; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Faure-Dupuy S; Department of Infectious Diseases, Molecular Virology, Heidelberg University, Heidelberg, Germany.
Liver Int ; 41(11): 2547-2559, 2021 11.
Article en En | MEDLINE | ID: mdl-34520597
ABSTRACT
In their never-ending quest towards persistence within their host, hepatitis viruses have developed numerous ways to counteract the liver innate immunity. This review highlights the different and common mechanisms employed by these viruses to (i) establish in the liver (passive entry or active evasion from immune recognition) and (ii) actively inhibit the innate immune response (ie modulation of pattern recognition receptor expression and/or signalling pathways, modulation of interferon response and modulation of immune cells count or phenotype).
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Virus / Inmunidad Innata Idioma: En Revista: Liver Int Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Francia

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Virus / Inmunidad Innata Idioma: En Revista: Liver Int Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Francia