GPCR-mediated EGFR transactivation ameliorates skin toxicities induced by afatinib.

Chen, Le-Ying; You, Qing; Lv, Da-Zhao; Li, Shuai-Hu; Zhang, Shi-Yi

Chen, Le-Ying; You, Qing; Lv, Da-Zhao; Li, Shuai-Hu; Zhang, Shi-Yi.

Afiliación

Chen LY; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
You Q; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Lv DZ; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Li SH; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Zhang SY; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China. zhangshiyi@sjtu.edu.cn.

Acta Pharmacol Sin ; 43(6): 1534-1543, 2022 Jun.

Article en En | MEDLINE | ID: mdl-34552215

Asunto(s)

Exantema; Enfermedades de la Piel; Afatinib; Animales; Receptores ErbB; Humanos; Inhibidores de Proteínas Quinasas; Ratas; Receptores Acoplados a Proteínas G/metabolismo; Activación Transcripcional

Palabras clave

EGFR inhibitor; EGFR transactivation; GPCR agonist; rash.

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedades de la Piel / Exantema Límite: Animals / Humans Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China

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