IonFlow: a galaxy tool for the analysis of ionomics data sets.
Metabolomics
; 17(10): 91, 2021 09 25.
Article
en En
| MEDLINE
| ID: mdl-34562172
INTRODUCTION: Inductively coupled plasma mass spectrometry (ICP-MS) experiments generate complex multi-dimensional data sets that require specialist data analysis tools. OBJECTIVE: Here we describe tools to facilitate analysis of the ionome composed of high-throughput elemental profiling data. METHODS: IonFlow is a Galaxy tool written in R for ionomics data analysis and is freely accessible at https://github.com/wanchanglin/ionflow . It is designed as a pipeline that can process raw data to enable exploration and interpretation using multivariate statistical techniques and network-based algorithms, including principal components analysis, hierarchical clustering, relevance network extraction and analysis, and gene set enrichment analysis. RESULTS AND CONCLUSION: The pipeline is described and tested on two benchmark data sets of the haploid S. Cerevisiae ionome and of the human HeLa cell ionome.
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MEDLINE
Asunto principal:
Saccharomyces cerevisiae
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Humans
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En
Revista:
Metabolomics
Año:
2021
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Article