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Structural basis for isoform-specific inhibition of human CTPS1.
Lynch, Eric M; DiMattia, Michael A; Albanese, Steven; van Zundert, Gydo C P; Hansen, Jesse M; Quispe, Joel D; Kennedy, Madison A; Verras, Andreas; Borrelli, Kenneth; Toms, Angela V; Kaila, Neelu; Kreutter, Kevin D; McElwee, Joshua J; Kollman, Justin M.
Afiliación
  • Lynch EM; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • DiMattia MA; Schrödinger, New York, NY 10036.
  • Albanese S; Schrödinger, New York, NY 10036.
  • van Zundert GCP; Schrödinger, New York, NY 10036.
  • Hansen JM; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Quispe JD; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Kennedy MA; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Verras A; Schrödinger, New York, NY 10036.
  • Borrelli K; Schrödinger, New York, NY 10036.
  • Toms AV; Nimbus Therapeutics, Cambridge, MA 02139.
  • Kaila N; Nimbus Therapeutics, Cambridge, MA 02139.
  • Kreutter KD; Nimbus Therapeutics, Cambridge, MA 02139.
  • McElwee JJ; Nimbus Therapeutics, Cambridge, MA 02139.
  • Kollman JM; Department of Biochemistry, University of Washington, Seattle, WA 98195; jkoll@uw.edu.
Proc Natl Acad Sci U S A ; 118(40)2021 10 05.
Article en En | MEDLINE | ID: mdl-34583994
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ligasas de Carbono-Nitrógeno / Isoformas de Proteínas Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ligasas de Carbono-Nitrógeno / Isoformas de Proteínas Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article