Systematic review and meta-analysis on effectiveness and safety of the full-thickness resection device (FTRD) in the colon.
Z Gastroenterol
; 60(5): 741-752, 2022 May.
Article
en En
| MEDLINE
| ID: mdl-34587628
ABSTRACT
BACKGROUND:
Endoscopic full-thickness resection (EFTR) has expanded the possibilities of endoscopic resection. The full-thickness resection device (FTRD, Ovesco Endoscopy, Tübingen, Germany) combines a clip-based defect closure and snare resection in a single device.METHODS:
Systematic review and meta-analysis on effectiveness and safety of the FTRD in the colon.RESULTS:
A total of 26 studies (12 published as full-text articles and 14 conference papers) with 1538 FTRD procedures were included. The pooled estimate for reaching the target lesion was 96.1â% (95â% confidence interval [95â% CI] 94.6-97.1) and 90.0â% (95â% CI 87.0-92.3) for technically successful resection. Pooled estimate of histologically complete resection was 77.8â% (95â% CI 74.7-80.6). Adverse events occurred at a pooled estimate rate of 8.0â% (95â% CI 5.8-10.4). Pooled estimates for bleeding and perforation were 1.5â% (95â% CI 0.3-3.3) and 0.3â% (95â% CI 0.0-0.9), respectively. The rate for need of emergency surgery after FTRD was 1.0â% (95â% CI 0.4-1.8).CONCLUSION:
The use of the FTRD in the colon shows very high rates of technical success and complete resection (R0) as well as a low risk of adverse events. Emergency surgery after colonic FTRD resection is necessary in single cases only.
Texto completo:
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Bases de datos:
MEDLINE
Asunto principal:
Adenoma
/
Resección Endoscópica de la Mucosa
Tipo de estudio:
Observational_studies
/
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Z Gastroenterol
Año:
2022
Tipo del documento:
Article
País de afiliación:
Alemania