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Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors.
Meng, Xiang-Dong; Gao, Li-Xin; Wang, Zhi-Jia; Feng, Bo; Zhang, Chun; Satheeshkumar, Rajendran; Li, Jia; Zhu, Yun-Long; Zhou, Yu-Bo; Wang, Wen-Long.
Afiliación
  • Meng XD; School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China.
  • Gao LX; School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China; State key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Wang ZJ; School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China.
  • Feng B; State key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Zhongshan Institute for Drug Discovery, Institutes of Drug Discovery and Development, Chinese Academy of Sciences, Zhongshan 528400, China.
  • Zhang C; School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China; School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
  • Satheeshkumar R; Department of Organic Chemistry, Faculty of Chemistry and Pharmacy, Pontifical Catholic University of Chile, Santiago 702843, Chile.
  • Li J; State key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhu YL; The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi 214002, China. Electronic address: sequoia113847@163.com.
  • Zhou YB; State key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Zhongshan Institute for Drug Discovery, Institutes of Drug Discovery and Development, Chinese Academy of Sciences, Zhongshan 528400, China. Electronic address: ybzhou@sim
  • Wang WL; School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China. Electronic address: wwenlong2011@163.com.
Bioorg Chem ; 116: 105384, 2021 11.
Article en En | MEDLINE | ID: mdl-34601294
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oxadiazoles / Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 11 / Antineoplásicos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oxadiazoles / Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 11 / Antineoplásicos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2021 Tipo del documento: Article País de afiliación: China