D-dimer levels for Risk Stratification in Patients with Suspected COVID-19 - A Prospective Observational Study.
Acute Med
; 20(3): 193-203, 2021.
Article
en En
| MEDLINE
| ID: mdl-34679137
ABSTRACT
BACKGROUND:
Elevated D-dimer levels have been observed in COVID-19 and are of prognostic value, but have not been compared to an appropriate control group.METHODS:
Observational cohort study including emergency patients with suspected or confirmed COVID-19. Logistic regression defined the association of D-dimer levels, COVID-19 positivity, age, and gender with 30-day-mortality.RESULTS:
953 consecutive patients (median age 58, 43% women) presented with suspected COVID-19 12 (7.4%) patients with confirmed SARS-CoV-2-infection died, compared with 28 (3.5%) patients without SARS-CoV-2-infection. Overall, most (56%) patients had elevated D-dimer levels (≥0.5mg/l). Age (OR 1.07, CI 1.05-1.10), D-dimer levels ≥0.5mg/l (OR 2.44, CI 0.98-7.39), and COVID-19 (OR 2.79, CI 1.28-5.80) were associated with 30-day-mortality.CONCLUSION:
D-dimer levels are effective prognosticators in both patient groups.
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Bases de datos:
MEDLINE
Asunto principal:
COVID-19
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Acute Med
Año:
2021
Tipo del documento:
Article
País de afiliación:
Suiza