[Nausea and vomiting in pregnancy: A place for ondansetron?] / Nausées et vomissements gravidiques : quelle place pour l'ondansétron ?
Gynecol Obstet Fertil Senol
; 49(12): 947-950, 2021 12.
Article
en Fr
| MEDLINE
| ID: mdl-34700033
ABSTRACT
Although there is no recommendation in France relating to the treatment of nausea and vomiting of pregnancy, there are some in other countries, where ondansetron, widely used, appears to be an effective second-line treatment option behind doxylamine/vitamin B6 association and metoclopramide. However, based on some recent publication suggesting an increased risk of orofacial clefts and congenital heart defects in fetuses exposed in utero to ondansetron in the 1st trimester of pregnancy, the European Medicines Agency now states that this drug should not longer be used during this period. This 2019 decision is controversial and whether ondansetron can be used in pregnant women with severe vomiting during pregnancy is still in question.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Labio Leporino
/
Fisura del Paladar
/
Antieméticos
Tipo de estudio:
Guideline
Límite:
Female
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Humans
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Pregnancy
Idioma:
Fr
Revista:
Gynecol Obstet Fertil Senol
Año:
2021
Tipo del documento:
Article