MELAS syndrome: an acute stroke-like episode complicated by renal tubular acidosis.
BMJ Case Rep
; 14(11)2021 Nov 02.
Article
en En
| MEDLINE
| ID: mdl-34728512
ABSTRACT
MELAS, a mitochondrially inherited multisystem disorder, can present with acute stroke-like episodes. The literature thus far supports the use of L-arginine therapy in acute MELAS flares to alleviate and shorten the duration of symptoms. This is the case of a patient who presented with ataxia and worsening confusion on a background of genetically confirmed MELAS syndrome. In this instance, intravenous L-arginine therapy, along with corticosteroids, was administered in keeping with best practice. However, in a metabolically vulnerable patient, L-arginine therapy resulted in a further deterioration in his clinical status and the development of a non-anion gap metabolic acidosis.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Acidosis Tubular Renal
/
Síndrome MELAS
/
Accidente Cerebrovascular
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Guideline
Límite:
Humans
Idioma:
En
Revista:
BMJ Case Rep
Año:
2021
Tipo del documento:
Article
País de afiliación:
Irlanda