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Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases.
Ritchie, Scott C; Lambert, Samuel A; Arnold, Matthew; Teo, Shu Mei; Lim, Sol; Scepanovic, Petar; Marten, Jonathan; Zahid, Sohail; Chaffin, Mark; Liu, Yingying; Abraham, Gad; Ouwehand, Willem H; Roberts, David J; Watkins, Nicholas A; Drew, Brian G; Calkin, Anna C; Di Angelantonio, Emanuele; Soranzo, Nicole; Burgess, Stephen; Chapman, Michael; Kathiresan, Sekar; Khera, Amit V; Danesh, John; Butterworth, Adam S; Inouye, Michael.
Afiliación
  • Ritchie SC; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. sr827@medschl.cam.ac.uk.
  • Lambert SA; Cambridge Baker Systems Genomics Initiative, Baker Heart & Diabetes Institute, Melbourne, Victoria, Australia. sr827@medschl.cam.ac.uk.
  • Arnold M; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. sr827@medschl.cam.ac.uk.
  • Teo SM; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK. sr827@medschl.cam.ac.uk.
  • Lim S; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Scepanovic P; Cambridge Baker Systems Genomics Initiative, Baker Heart & Diabetes Institute, Melbourne, Victoria, Australia.
  • Marten J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Zahid S; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.
  • Chaffin M; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Liu Y; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Abraham G; Cambridge Baker Systems Genomics Initiative, Baker Heart & Diabetes Institute, Melbourne, Victoria, Australia.
  • Ouwehand WH; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Roberts DJ; Cambridge Baker Systems Genomics Initiative, Baker Heart & Diabetes Institute, Melbourne, Victoria, Australia.
  • Watkins NA; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Drew BG; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Calkin AC; Cambridge Baker Systems Genomics Initiative, Baker Heart & Diabetes Institute, Melbourne, Victoria, Australia.
  • Di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Soranzo N; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Burgess S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Chapman M; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Kathiresan S; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Khera AV; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Danesh J; Lipid Metabolism & Cardiometabolic Disease Laboratory, Baker Heart & Diabetes Institute, Melbourne, Victoria, Australia.
  • Butterworth AS; Molecular Metabolism & Ageing Laboratory, Baker Heart & Diabetes Institute, Melbourne, Victoria, Australia.
  • Inouye M; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Nat Metab ; 3(11): 1476-1483, 2021 11.
Article en En | MEDLINE | ID: mdl-34750571
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Sanguíneas / Herencia Multifactorial / Proteoma / Cardiopatías / Enfermedades Metabólicas Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Nat Metab Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Sanguíneas / Herencia Multifactorial / Proteoma / Cardiopatías / Enfermedades Metabólicas Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Nat Metab Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido