Contributions of side effects to contraceptive discontinuation and method switch among Kenyan women: a prospective cohort study.
BJOG
; 129(6): 926-937, 2022 May.
Article
en En
| MEDLINE
| ID: mdl-34839583
ABSTRACT
OBJECTIVE:
To determine the contribution of specific contraceptive side effects to method switch and modern-method discontinuation among Kenyan women.DESIGN:
A prospective cohort study.SETTING:
Five counties in Western Kenya.PARTICIPANTS:
Women aged ≥18 years old and emancipated female minors ≥14 years old using modern, reversible contraception were recruited while attending 10 public health facilities.METHODS:
Patient-reported adverse effect symptoms, method switch and discontinuation were reported through weekly text message-based surveys for 24 weeks. MAIN OUTCOME MEASUREMENTS Prevalence, hazards ratio (HR).RESULTS:
Among 825 women, 44% were using implants, 43% injectables, 7% an intrauterine device and 6% oral contraceptive pills at enrolment. Most (61%) women were continuing a method used in the previous month. During the 24-week follow up, incidence of contraceptive switch was 61.3 per 100 person-years (95% confidence interval [CI] 52.4-71.8) and incidence of discontinuation was 38.5 per 100 person-years (95% CI 31.6-47.0). On average, one-quarter (prevalence [Pr] 0.24, 95% CI 0.22-0.26) of participants reported side effects or method problems weekly, with sexual side effects the most prevalent symptom (Pr 0.15, 95% CI 0.13-0.16). Lack of expected bleeding was associated with higher risk of method switch (adjusted hazard ratio [aHR] 2.36, 95% CI 1.22-4.57). Risk of all-modern method discontinuation was higher among women experiencing irregular bleeding (aHR 2.39, 95% CI 1.20-4.77), weight changes (aHR 2.72, 95% CI 1.47-4.68) and sexual side effects (aHR 2.42, 95% CI 1.40-4.20).CONCLUSIONS:
Addressing irregular bleeding, weight changes and sexual side effects through development of new products that minimise these specific side effects and anticipatory counseling may reduce method-related discontinuation. TWEETABLE ABSTRACT Bleeding, weight changes, sexual problems associated with discontinuation of #contraception, but many continue despite side effects.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Anticoncepción
/
Conducta Anticonceptiva
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
País/Región como asunto:
Africa
Idioma:
En
Revista:
BJOG
Asunto de la revista:
GINECOLOGIA
/
OBSTETRICIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Estados Unidos