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Total synthesis of remdesivir.
Kumar Palli, Kishore; Ghosh, Palash; Krishna Avula, Shiva; Sridhara Shanmukha Rao, B; Patil, Amol D; Ghosh, Subhash; Sudhakar, Gangarajula; Raji Reddy, Chada; Mainkar, Prathama S; Chandrasekhar, Srivari.
Afiliación
  • Kumar Palli K; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad 500007, India.
  • Ghosh P; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Krishna Avula S; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad 500007, India.
  • Sridhara Shanmukha Rao B; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Patil AD; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad 500007, India.
  • Ghosh S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Sudhakar G; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad 500007, India.
  • Raji Reddy C; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Mainkar PS; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad 500007, India.
  • Chandrasekhar S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
Tetrahedron Lett ; 88: 153590, 2022 Jan 05.
Article en En | MEDLINE | ID: mdl-34908617
ABSTRACT
Remdesivir, the first drug approved by the FDA to treat COVID-19, is in high demand for patients infected with the SARS-CoV-2 virus. Herein, we report a facile approach minimizing the protecting group manipulations to afford remdesivir in good overall yield.
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Tetrahedron Lett Año: 2022 Tipo del documento: Article País de afiliación: India
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Tetrahedron Lett Año: 2022 Tipo del documento: Article País de afiliación: India