(E), envelope; (M), membrane; (N), nucleocapsid; (S), Spike; ACE2, Angiotensin Converting Enzyme 2; BLAST, Basic Local Alignment Search Tool; CD4, Helper T lymphocytes express cluster determinant 4; CD8, cytotoxic T cells express cluster determinant 8; CDC, Centers of Disease Control; COVID-19; COVID-19, Corona Virus Disease 2019; Coronavirus; Del, Deletion; Genomics; Ins, Insertion; MDCK, Madin-Darby Canine Kidney; MERS-CoV, Middle East Respiratory Syndrome Coronavirus; NCBI, National Center for Biotechnology Information; NJ, neighbor-joining; NSP, nonstructural protein; NTD,  N-Terminal Domain; ORF, Open Reading Frame; PCR, polymerase chain reaction; PID, percentage identity; Proteomics; RBD, receptor binding domain; SARS-COV-2; SARS-CoV-1, Severe Acute Respiratory Syndrome Coronavirus 1; SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2; UTR, Untranslated region; VOC, variants of concern; Vaccines; WHO, World Health Organization; mAbs, monoclonal antibodies