Di-(2-ethylhexyl) phthalate triggers DNA methyltransferase 1 expression resulting in elevated CpG-methylation and enrichment of MECP2 in the p21 promoter in vitro.

Ghosh, Krishna; Chatterjee, Biji; Nalla, KiranKumar; Behera, Bablu; Mukherjee, Amit; Kanade, Santosh R

Ghosh, Krishna; Chatterjee, Biji; Nalla, KiranKumar; Behera, Bablu; Mukherjee, Amit; Kanade, Santosh R.

Afiliación

Ghosh K; Department of Biochemistry and Molecular Biology, School of Biological Sciences, Central University of Kerala, Kasaragod, 671316, Kerala, India.
Chatterjee B; Department of Biochemistry and Molecular Biology, School of Biological Sciences, Central University of Kerala, Kasaragod, 671316, Kerala, India.
Nalla K; Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Central University P.O., Hyderabad, 500046, Telangana, India.
Behera B; Department of Biochemistry and Molecular Biology, School of Biological Sciences, Central University of Kerala, Kasaragod, 671316, Kerala, India.
Mukherjee A; Rajiv Gandhi Centre for Diabetes and Endocrinology, JN Medical College, Aligarh Muslim University, Aligarh, 202002, Uttar Pradesh, India.
Kanade SR; Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Central University P.O., Hyderabad, 500046, Telangana, India. Electronic address: san@uohyd.ac.in.

Chemosphere ; 293: 133569, 2022 Apr.

Article en En | MEDLINE | ID: mdl-35033518

Asunto(s)

Dietilhexil Ftalato; Ácidos Ftálicos; Metilación de ADN; Dietilhexil Ftalato/toxicidad; Humanos; Regiones Promotoras Genéticas

Palabras clave

DEHP; DNMT1; E2F1; MECP2; SP1; TET1; p21; p53

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ácidos Ftálicos / Dietilhexil Ftalato Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Chemosphere Año: 2022 Tipo del documento: Article País de afiliación: India

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