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Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins.
Mottin, Melina; Caesar, Lindsay K; Brodsky, David; Mesquita, Nathalya C M R; de Oliveira, Ketllyn Zagato; Noske, Gabriela Dias; Sousa, Bruna K P; Ramos, Paulo R P S; Jarmer, Hannah; Loh, Bonnie; Zorn, Kimberley M; Foil, Daniel H; Torres, Pedro M; Guido, Rafael V C; Oliva, Glaucius; Scholle, Frank; Ekins, Sean; Cech, Nadja B; Andrade, Carolina H; Laster, Scott M.
Afiliación
  • Mottin M; Laboratory of Molecular Modeling and Drug Design, LabMol, Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO, Brazil; Laboratório de Interação Patógeno-Hospedeiro, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, Brazil.
  • Caesar LK; Department of Chemistry & Biochemistry, University of North Carolina Greensboro, NC, USA.
  • Brodsky D; Department of Biological Sciences, and the Comparative Medicine Institute CAVE Program, North Carolina State University, Raleigh, NC, USA.
  • Mesquita NCMR; São Carlos Institute of Physics, University of São Paulo, São Carlos, SP, Brazil.
  • de Oliveira KZ; São Carlos Institute of Physics, University of São Paulo, São Carlos, SP, Brazil.
  • Noske GD; Department of Biological Sciences, and the Comparative Medicine Institute CAVE Program, North Carolina State University, Raleigh, NC, USA.
  • Sousa BKP; Laboratory of Molecular Modeling and Drug Design, LabMol, Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO, Brazil.
  • Ramos PRPS; Laboratory of Molecular Modeling and Drug Design, LabMol, Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO, Brazil.
  • Jarmer H; Department of Biological Sciences, and the Comparative Medicine Institute CAVE Program, North Carolina State University, Raleigh, NC, USA.
  • Loh B; Department of Biological Sciences, and the Comparative Medicine Institute CAVE Program, North Carolina State University, Raleigh, NC, USA.
  • Zorn KM; Collaborations Pharmaceuticals, Inc, NC, USA.
  • Foil DH; Collaborations Pharmaceuticals, Inc, NC, USA.
  • Torres PM; Laboratório de Modelagem e Dinâmica Molecular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
  • Guido RVC; São Carlos Institute of Physics, University of São Paulo, São Carlos, SP, Brazil.
  • Oliva G; São Carlos Institute of Physics, University of São Paulo, São Carlos, SP, Brazil.
  • Scholle F; Department of Biological Sciences, and the Comparative Medicine Institute CAVE Program, North Carolina State University, Raleigh, NC, USA.
  • Ekins S; Collaborations Pharmaceuticals, Inc, NC, USA.
  • Cech NB; Department of Chemistry & Biochemistry, University of North Carolina Greensboro, NC, USA.
  • Andrade CH; Laboratory of Molecular Modeling and Drug Design, LabMol, Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO, Brazil. Electronic address: carolina@ufg.br.
  • Laster SM; Department of Biological Sciences, and the Comparative Medicine Institute CAVE Program, North Carolina State University, Raleigh, NC, USA. Electronic address: smlaster@ncsu.edu.
Bioorg Chem ; 120: 105649, 2022 03.
Article en En | MEDLINE | ID: mdl-35124513
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Chalcona / Angelica / Chalconas / Virus Zika / Infección por el Virus Zika Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Bioorg Chem Año: 2022 Tipo del documento: Article País de afiliación: Brasil
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Chalcona / Angelica / Chalconas / Virus Zika / Infección por el Virus Zika Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Bioorg Chem Año: 2022 Tipo del documento: Article País de afiliación: Brasil