A TIReless battle: TIR domains in plant-pathogen interactions.

Liu, Jinbao; Fakhar, Ali Zeeshan; Pajerowska-Mukhtar, Karolina M; Mukhtar, M Shahid

Liu, Jinbao; Fakhar, Ali Zeeshan; Pajerowska-Mukhtar, Karolina M; Mukhtar, M Shahid.

Afiliación

Liu J; Department of Biology, University of Alabama at Birmingham, 1300 University Boulevard, Birmingham, AL 35294, USA.
Fakhar AZ; Department of Biology, University of Alabama at Birmingham, 1300 University Boulevard, Birmingham, AL 35294, USA.
Pajerowska-Mukhtar KM; Department of Biology, University of Alabama at Birmingham, 1300 University Boulevard, Birmingham, AL 35294, USA.
Mukhtar MS; Department of Biology, University of Alabama at Birmingham, 1300 University Boulevard, Birmingham, AL 35294, USA. Electronic address: smukhtar@uab.edu.

Trends Plant Sci ; 27(5): 426-429, 2022 05.

Article en En | MEDLINE | ID: mdl-35177315

ABSTRACT

ABSTRACT

Toll/interleukin-1 receptor (TIR) domain-containing proteins are conserved across kingdoms, and their mechanistic understanding holds promise for basic plant biology and agriculture. Here, we discuss the novel enzymatic TIR domain functions of nucleotide-binding leucine-rich repeat receptors (NLRs) in cell death, and posit how TIR domain-containing effectors mechanistically subvert host immune systems.

Asunto(s)

Proteínas de Arabidopsis; Arabidopsis; Arabidopsis/metabolismo; Proteínas de Arabidopsis/metabolismo; Muerte Celular; Plantas/genética; Plantas/metabolismo; Dominios Proteicos

Palabras clave

2',3'-cAMP/cGMP synthetase; HopAM1; NADase; Toll/interleukin-1 receptor/TIR; cell death; v-cADPR

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Arabidopsis / Proteínas de Arabidopsis Idioma: En Revista: Trends Plant Sci Asunto de la revista: BOTANICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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