Quo vadis, neutrophil?

Gonzalez, Rodrigo J; von Andrian, Ulrich H

Gonzalez, Rodrigo J; von Andrian, Ulrich H.

Afiliación

Gonzalez RJ; Department of Immunology, Harvard Medical School, Boston, MA, USA; The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
von Andrian UH; Department of Immunology, Harvard Medical School, Boston, MA, USA; The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA. Electronic address: uva@hms.harvard.edu.

Cell ; 185(5): 759-761, 2022 03 03.

Article en En | MEDLINE | ID: mdl-35245478

RESUMEN

Neutrophil recruitment from blood into tissues is a hallmark of inflammation and anti-microbial host defense. In this issue, De Giovanni et al. describe an unanticipated role for a serotonin metabolite, 5-HIAA, which is produced by activated platelets and mast cells and engages the orphan receptor, GPR35, to recruit neutrophils to inflamed tissues.

Asunto(s)

Plaquetas; Neutrófilos; Plaquetas/metabolismo; Humanos; Inflamación/metabolismo; Mastocitos/metabolismo; Infiltración Neutrófila; Neutrófilos/metabolismo

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Plaquetas / Neutrófilos Límite: Humans Idioma: En Revista: Cell Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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