Stimulating the Hematopoietic Effect of Simulated Digestive Product of Fucoidan from <i>Sargassum fusiforme</i> on Cyclophosphamide-Induced Hematopoietic Damage in Mice and Its Protective Mechanisms Based on Serum Lipidomics.

Ma, Wei-Ping; Yin, Shi-Ning; Chen, Jia-Peng; Geng, Xi-Cheng; Liu, Ming-Fei; Li, Hai-Hua; Liu, Ming; Liu, Hong-Bing

Stimulating the Hematopoietic Effect of Simulated Digestive Product of Fucoidan from Sargassum fusiforme on Cyclophosphamide-Induced Hematopoietic Damage in Mice and Its Protective Mechanisms Based on Serum Lipidomics.

Ma, Wei-Ping; Yin, Shi-Ning; Chen, Jia-Peng; Geng, Xi-Cheng; Liu, Ming-Fei; Li, Hai-Hua; Liu, Ming; Liu, Hong-Bing.

Afiliación

Ma WP; Key Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Yin SN; Qingdao Institute for Food and Drug Control, Qingdao 266000, China.
Chen JP; NMPA Key Laboratory for Quality Research and Evaluation of Marine Traditional Chinese Medicine, Qingdao 266000, China.
Geng XC; Key Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Liu MF; Key Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Li HH; Key Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Liu M; Key Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Liu HB; Key Laboratory of Marine Drugs, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

Mar Drugs ; 20(3)2022 Mar 09.

Article en En | MEDLINE | ID: mdl-35323500

Asunto(s)

Ciclofosfamida/toxicidad; Hematopoyesis/efectos de los fármacos; Agonistas Mieloablativos/toxicidad; Polisacáridos/farmacología; Sustancias Protectoras/farmacología; Sargassum; Animales; Biomarcadores/sangre; Médula Ósea/efectos de los fármacos; Médula Ósea/metabolismo; Proliferación Celular/efectos de los fármacos; ADN/metabolismo; Humanos; Células K562; Recuento de Leucocitos; Lipidómica; Ratones; Neutrófilos/efectos de los fármacos; Recuento de Plaquetas

Palabras clave

Sargassum fusiforme fucoidan; hematopoietic damage; lipidomics

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polisacáridos / Agonistas Mieloablativos / Sustancias Protectoras / Ciclofosfamida / Sargassum / Hematopoyesis Límite: Animals / Humans Idioma: En Revista: Mar Drugs Asunto de la revista: BIOLOGIA / FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China

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