Real-world prevalence of endoscopic findings in patients with gastroesophageal reflux symptoms: a cross-sectional study.
Endosc Int Open
; 10(4): E342-E346, 2022 Apr.
Article
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| MEDLINE
| ID: mdl-35433201
ABSTRACT
Background and study aims Data regarding endoscopic findings and symptom correlation in patients with gastroesophageal reflux disease (GERD) symptoms are largely limited to single-center experiences. We performed a nationwide study to examine the association between patient-reported GERD symptoms and clinically relevant endoscopic findings. Patients and methods Using the National Endoscopic Database, we retrospectively identified all esophagogastroduodenoscopies (EGDs) performed for GERD symptoms from 2000 to 2014.âPatients were categorized into three symptom groups 1) typical reflux only (R); 2) airway only (A); and 3) both R and A (Râ+âA). Outcomes were the point prevalence of endoscopic findings in relation to patient-reported GERD symptom groups. Statistical analyses were performed using R. Results A total of 167,459 EGDs were included 96.8â% for R symptoms, 1.4â% for A symptoms, and 1.8â% for Râ+âA symptoms. Of the patients, 13.4â% had reflux esophagitis (RE), 9.0â% Barrett's esophagus (BE), and 45.4â% hiatal hernia (HH). The Râ+âA group had a significantly higher point prevalence of RE (21.6â% vs. 13.3â% and 12â%; P â<â0.005) and HH (56.9â% vs. 45.3â% and 38.3â%; P â<â0.005) compared to the R or A groups, respectively. The R group had a significantly higher point prevalence of BE compared to the A or Râ+âA groups, respectively (9.1â% vs. 6.1â% and 6.1â%, P â<â0.005). Conclusions On a national level, patients experiencing Râ+âA GERD symptoms appear more likely to have RE and HH, while those with only R symptoms appear more likely to have BE. These real-world data may help guide how providers and institutions approach acid-suppression therapy, set thresholds for recommending EGD, and develop management algorithms.
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Bases de datos:
MEDLINE
Tipo de estudio:
Diagnostic_studies
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Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
Endosc Int Open
Año:
2022
Tipo del documento:
Article
País de afiliación:
Estados Unidos