Aspergillus awamori attenuates ochratoxin A-induced renal and cardiac injuries in rabbits by activating the Nrf2/HO-1 signaling pathway and downregulating IL1ß, TNF&#945;, and iNOS gene expressions.

Assar, Doaa H; Asa, Samah Abou; El-Abasy, Moshira A; Elbialy, Zizy I; Shukry, Mustafa; Latif, Amera Abd El; BinMowyna, Mona N; Althobaiti, Norah A; El-Magd, Mohammed A

Aspergillus awamori attenuates ochratoxin A-induced renal and cardiac injuries in rabbits by activating the Nrf2/HO-1 signaling pathway and downregulating IL1ß, TNFα, and iNOS gene expressions.

Assar, Doaa H; Asa, Samah Abou; El-Abasy, Moshira A; Elbialy, Zizy I; Shukry, Mustafa; Latif, Amera Abd El; BinMowyna, Mona N; Althobaiti, Norah A; El-Magd, Mohammed A.

Afiliación

Assar DH; Clinical Pathology Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh, 33516, Egypt.
Asa SA; Pathology Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh, 33516, Egypt.
El-Abasy MA; Poultry and Rabbit Diseases Department, Faculty of Veterinary Medicine, Kafr El-Sheikh University, Kafr El-Sheikh, 33516, Egypt.
Elbialy ZI; Fish Processing and Biotechnology Department, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, 33516, Kafr El-Sheikh, Egypt. zeze_elsayed@fsh.kfs.edu.eg.
Shukry M; Physiology Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh, 33516, Egypt.
Latif AAE; Department of Pharmacology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh, 33516, Egypt.
BinMowyna MN; College of Applied Medical Sciences, Shaqra University, Shaqra, Saudi Arabia.
Althobaiti NA; Biology Department, College of Science and Humanities-Al Quwaiiyah, Shaqra University, Al Quwaiiyah, 19257, Saudi Arabia.
El-Magd MA; Anatomy and Embryology Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh, 33516, Egypt.

Environ Sci Pollut Res Int ; 29(46): 69798-69817, 2022 Oct.

Article en En | MEDLINE | ID: mdl-35576029

Asunto(s)

Antioxidantes; Factor 2 Relacionado con NF-E2; Animales; Masculino; Conejos; Fosfatasa Alcalina/metabolismo; Antioxidantes/metabolismo; Aspergillus; Biomarcadores/metabolismo; Creatinina/metabolismo; Radicales Libres/metabolismo; Expresión Génica; Riñón; Factor 2 Relacionado con NF-E2/metabolismo; Ocratoxinas; Estrés Oxidativo; Sustancias Protectoras/farmacología; Transducción de Señal; Superóxido Dismutasa/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo; Urea/metabolismo

Palabras clave

Aspergillus awamori; Gene expression; Histopathology; Ochratoxin A; Oxidative stress

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Factor 2 Relacionado con NF-E2 / Antioxidantes Límite: Animals Idioma: En Revista: Environ Sci Pollut Res Int Asunto de la revista: SAUDE AMBIENTAL / TOXICOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Egipto

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