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Associations of a polygenic risk score with coronary artery disease phenotypes in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.
Newman, Jonathan D; Douglas, Pamela S; Zhbannikov, Ilya; Ferencik, Maros; Foldyna, Borek; Hoffmann, Udo; Shah, Svati H; Ginsburg, Geoffrey S; Lu, Michael T; Voora, Deepak.
Afiliación
  • Newman JD; The Leon H Charney Division of Cardiology, The Center for the Prevention of Cardiovascular Disease, New York, NY 10016. Electronic address: Jonathan.Newman@nyumc.org.
  • Douglas PS; The Leon H Charney Division of Cardiology, The Center for the Prevention of Cardiovascular Disease, New York, NY 10016.
  • Zhbannikov I; The Leon H Charney Division of Cardiology, The Center for the Prevention of Cardiovascular Disease, New York, NY 10016.
  • Ferencik M; The Leon H Charney Division of Cardiology, The Center for the Prevention of Cardiovascular Disease, New York, NY 10016.
  • Foldyna B; The Leon H Charney Division of Cardiology, The Center for the Prevention of Cardiovascular Disease, New York, NY 10016.
  • Hoffmann U; The Leon H Charney Division of Cardiology, The Center for the Prevention of Cardiovascular Disease, New York, NY 10016.
  • Shah SH; The Leon H Charney Division of Cardiology, The Center for the Prevention of Cardiovascular Disease, New York, NY 10016.
  • Ginsburg GS; The Leon H Charney Division of Cardiology, The Center for the Prevention of Cardiovascular Disease, New York, NY 10016.
  • Lu MT; The Leon H Charney Division of Cardiology, The Center for the Prevention of Cardiovascular Disease, New York, NY 10016.
  • Voora D; The Leon H Charney Division of Cardiology, The Center for the Prevention of Cardiovascular Disease, New York, NY 10016.
Am Heart J ; 252: 12-15, 2022 10.
Article en En | MEDLINE | ID: mdl-35605652
ABSTRACT
A polygenic risk score (PGS) is associated with obstructive coronary artery disease (CAD) independent of traditional risk factors. Coronary computed tomography angiography (CTA) can characterize coronary plaques, including features of highrisk CAD. However, it is unknown if a PGS is associated with obstructive CAD and high-risk CAD phenotypes in patients with symptoms suggestive of CAD.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Am Heart J Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Am Heart J Año: 2022 Tipo del documento: Article