Differences in H3K4me3 and chromatin accessibility contribute to altered T-cell receptor signaling in neonatal naïve CD4 T cells.

Bermick, Jennifer R; Issuree, Priya; denDekker, Aaron; Gallagher, Katherine A; Santillan, Donna; Kunkel, Steven; Lukacs, Nicholas; Schaller, Matthew

Bermick, Jennifer R; Issuree, Priya; denDekker, Aaron; Gallagher, Katherine A; Santillan, Donna; Kunkel, Steven; Lukacs, Nicholas; Schaller, Matthew.

Afiliación

Bermick JR; Division of Neonatology, Department of Pediatrics, University of Iowa, Iowa City, IA, USA.
Issuree P; Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Michigan Medicine, Ann Arbor, MI, USA.
denDekker A; Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.
Gallagher KA; Department of Vascular Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Santillan D; Department of Vascular Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Kunkel S; Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA.
Lukacs N; Department of Pathology, Michigan Medicine, Ann Arbor, MI, USA.
Schaller M; Department of Pathology, Michigan Medicine, Ann Arbor, MI, USA.

Immunol Cell Biol ; 100(7): 562-579, 2022 08.

Article en En | MEDLINE | ID: mdl-35608955

Asunto(s)

Linfocitos T CD4-Positivos; Cromatina; Adulto; Cromatina/metabolismo; Histonas; Humanos; Recién Nacido; Activación de Linfocitos/genética; Receptores de Antígenos de Linfocitos T/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

ATAC-seq; ChIP-seq; T-cell receptor; T cell; epigenetics; neonate

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Cromatina / Linfocitos T CD4-Positivos Límite: Adult / Humans / Newborn Idioma: En Revista: Immunol Cell Biol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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