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Etiology and Clinical Patterns of Chronic Cough in the Chest Clinic of a Tertiary Hospital in Nigeria.
Desalu, Olufemi O; Ojuawo, Olutobi B; Aladesanmi, Adeniyi O; Adeoti, Adekunle O; Opeyemi, Christopher M; Oloyede, Taofeek; Afolayan, Oluwafemi J; Fawibe, Ademola E.
Afiliación
  • Desalu OO; Department of Medicine University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.
  • Ojuawo OB; Department of Medicine University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.
  • Aladesanmi AO; Department of Medicine University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.
  • Adeoti AO; Department of Medicine, Ekiti State University, Ado-Ekiti, Ekiti State, Nigeria.
  • Opeyemi CM; Department of Medicine University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.
  • Oloyede T; Department of Medicine, Federal Medical Centre, Katsina, Katsina State, Nigeria.
  • Afolayan OJ; Department of Medicine, Goulburn Valley Health, Shepparton, Victoria State, Australia.
  • Fawibe AE; Department of Medicine University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.
Int J Gen Med ; 15: 5285-5296, 2022.
Article en En | MEDLINE | ID: mdl-35655657
ABSTRACT

Purpose:

The burdens of chronic cough are mostly reported from Western and Asian countries. We aimed to determine the etiology and clinical patterns of chronic cough (CC) in the chest clinic of a tertiary hospital in Nigeria. Patients and

Methods:

This survey was a cross-sectional study of 218 patients. Chronic cough was defined as cough >8 weeks duration. The evaluation and diagnosis of patients was based on a diagnostic protocol developed from the international respiratory societies cough guidelines and a previous study.

Results:

The median age of patients was 50 years (interquartile range 30-68). One etiology was identified in 96.3% of cases; dual etiologies in 2.3%, and 1.4% had an unexplained cough. The most frequent causes of cough were COPD (33.5%), PTB (27.1%), and asthma (21.1%) which included 3 cases of cough variants of asthma (CVA). Other causes were post-tuberculosis lung disease (bronchiectasis and fibrosis) in 6.9%, lung cancer in 4.7%, and interstitial lung disease (ILD) in 3.2%. Gastroesophageal-related cough (GERC) accounted for <1.0%. Before the age of 45, the chronic cough was more frequent in the females than in the males, and the commonest cause was asthma, whereas, beyond age ≥ 45, the occurrence in males surpasses that of the females, and the commonest cause was COPD. Eighty-six percent reported shortness of breath as the most associated symptom. Systemic hypertension (15.6%) was the most frequent comorbidity, followed by HIV infection (3.7%). Chest radiograph, sputum GeneXpert MTB/RIF for TB, spirometry, and detailed history and trial of treatment, were enough to identify the cause in 72% of cases.

Conclusion:

The etiology and clinical patterns of chronic cough in this study are different from the western countries. When evaluating and managing chronic cough, clinicians in sub-Saharan Africa and TB endemic countries should consider these geographical variations in etiologies and clinical presentation.
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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Idioma: En Revista: Int J Gen Med Año: 2022 Tipo del documento: Article País de afiliación: Nigeria

Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Idioma: En Revista: Int J Gen Med Año: 2022 Tipo del documento: Article País de afiliación: Nigeria