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An Update on the Measurement of Motor Cerebellar Dysfunction in Multiple Sclerosis.
Kenyon, Katherine Hope; Boonstra, Frederique; Noffs, Gustavo; Butzkueven, Helmut; Vogel, Adam P; Kolbe, Scott; van der Walt, Anneke.
Afiliación
  • Kenyon KH; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia. katherine.kenyon@monash.edu.
  • Boonstra F; Centre for Neuroscience of Speech, University of Melbourne, Melbourne, VIC, Australia. katherine.kenyon@monash.edu.
  • Noffs G; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia.
  • Butzkueven H; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia.
  • Vogel AP; Centre for Neuroscience of Speech, University of Melbourne, Melbourne, VIC, Australia.
  • Kolbe S; Department of Neurology, Royal Melbourne Hospital, Melbourne, VIC, Australia.
  • van der Walt A; Redenlab Inc, Melbourne, VIC, Australia.
Cerebellum ; 22(4): 761-775, 2023 Aug.
Article en En | MEDLINE | ID: mdl-35761144
Multiple sclerosis (MS) is a progressive disease that often affects the cerebellum. It is characterised by demyelination, inflammation, and neurodegeneration within the central nervous system. Damage to the cerebellum in MS is associated with increased disability and decreased quality of life. Symptoms include gait and balance problems, motor speech disorder, upper limb dysfunction, and oculomotor difficulties. Monitoring symptoms is crucial for effective management of MS. A combination of clinical, neuroimaging, and task-based measures is generally used to diagnose and monitor MS. This paper reviews the present and new tools used by clinicians and researchers to assess cerebellar impairment in people with MS (pwMS). It also describes recent advances in digital and home-based monitoring for people with MS.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedades Cerebelosas / Esclerosis Múltiple Límite: Humans Idioma: En Revista: Cerebellum Asunto de la revista: CEREBRO Año: 2023 Tipo del documento: Article País de afiliación: Australia

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedades Cerebelosas / Esclerosis Múltiple Límite: Humans Idioma: En Revista: Cerebellum Asunto de la revista: CEREBRO Año: 2023 Tipo del documento: Article País de afiliación: Australia