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Time to re-evaluate the risks and benefits of valproate and a call for action.
Howes, Oliver D; Barnes, Thomas R E; Lennox, Belinda R; Markham, Sarah; Natesan, Sridhar.
Afiliación
  • Howes OD; Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK; and Faculty of Medicine, Institute of Clinical Sciences, Imperial College London, UK.
  • Barnes TRE; Faculty of Medicine, Department of Brain Sciences, Imperial College London, UK.
  • Lennox BR; Department of Psychiatry, University of Oxford, UK.
  • Markham S; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
  • Natesan S; Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK; and Faculty of Medicine, Institute of Clinical Sciences, Imperial College London, UK.
Br J Psychiatry ; 221(6): 711-713, 2022 12.
Article en En | MEDLINE | ID: mdl-35795925
Valproate is widely used in psychiatry and neurology, including off-label use. Here we consider its potential benefits and risks, particularly for women of childbearing potential, and the evidence that clinical guidelines are adhered to. Finally, we consider the implications for clinical practice and research into its efficacy in off-label indications.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ácido Valproico / Anticonvulsivantes Tipo de estudio: Etiology_studies / Guideline / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Br J Psychiatry Año: 2022 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ácido Valproico / Anticonvulsivantes Tipo de estudio: Etiology_studies / Guideline / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Br J Psychiatry Año: 2022 Tipo del documento: Article