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Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.
Kar, Siddhartha P; Quiros, Pedro M; Gu, Muxin; Jiang, Tao; Mitchell, Jonathan; Langdon, Ryan; Iyer, Vivek; Barcena, Clea; Vijayabaskar, M S; Fabre, Margarete A; Carter, Paul; Petrovski, Slavé; Burgess, Stephen; Vassiliou, George S.
Afiliación
  • Kar SP; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. siddhartha.kar@bristol.ac.uk.
  • Quiros PM; Section of Translational Epidemiology, Division of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. siddhartha.kar@bristol.ac.uk.
  • Gu M; Department of Haematology, Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK. pmquiros@ispasturias.es.
  • Jiang T; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. pmquiros@ispasturias.es.
  • Mitchell J; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain. pmquiros@ispasturias.es.
  • Langdon R; Department of Haematology, Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
  • Iyer V; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Barcena C; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge, Cambridge, UK.
  • Vijayabaskar MS; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Fabre MA; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Carter P; Section of Translational Epidemiology, Division of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Petrovski S; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Burgess S; Department of Haematology, Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
  • Vassiliou GS; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Nat Genet ; 54(8): 1155-1166, 2022 08.
Article en En | MEDLINE | ID: mdl-35835912
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Hematopoyesis Clonal / Hematopoyesis Tipo de estudio: Clinical_trials / Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Hematopoyesis Clonal / Hematopoyesis Tipo de estudio: Clinical_trials / Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido