Two new dammarane triterpenoid saponins from the leaves of Cyclocarya paliurus.
J Asian Nat Prod Res
; 25(5): 438-445, 2023 May.
Article
en En
| MEDLINE
| ID: mdl-35923147
ABSTRACT
Two undescribed dammarane triterpenoid saponins, cypaliurusides O and P (1 and 2), were isolated from the ethanol extracts of the leaves of Cyclocarya paliurus. Bioactivity assay results showed that compound 1 has potential cytotoxic activities against selected human cancer cell lines in vitro, with IC50 values ranging from 14.55 ± 0.55 to 22.75 ± 1.54 µM. Compound 1 showed better antitumor activity against HepG2 cells with IC50 of 14.55 ± 0.55 µM. In addition, compound 2 showed no obvious antitumor activity.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Saponinas
/
Triterpenos
/
Juglandaceae
Límite:
Humans
Idioma:
En
Revista:
J Asian Nat Prod Res
Asunto de la revista:
BOTANICA
/
QUIMICA
Año:
2023
Tipo del documento:
Article
País de afiliación:
China