DNA damage induces STING mediated IL-6-STAT3 survival pathway in triple-negative breast cancer cells and decreased survival of breast cancer patients.

Vasiyani, Hitesh; Mane, Minal; Rana, Khushboo; Shinde, Anjali; Roy, Milton; Singh, Jyoti; Gohel, Dhruv; Currim, Fatema; Srivastava, Ratika; Singh, Rajesh

Vasiyani, Hitesh; Mane, Minal; Rana, Khushboo; Shinde, Anjali; Roy, Milton; Singh, Jyoti; Gohel, Dhruv; Currim, Fatema; Srivastava, Ratika; Singh, Rajesh.

Afiliación

Vasiyani H; Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, 390002, India.
Mane M; Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, 390002, India.
Rana K; Department of Microbiology & Biotechnology Center, The M.S. University of Baroda, Vadodara, Gujarat, 390002, India.
Shinde A; Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, 390002, India.
Roy M; Institute for Cell Engineering, John Hopkins University School of Medicine, 733 North Broadway, MRB 731, Baltimore, MD, 21205, USA.
Singh J; Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, 390002, India.
Gohel D; Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, 390002, India.
Currim F; Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, 390002, India.
Srivastava R; Department of Microbiology & Biotechnology Center, The M.S. University of Baroda, Vadodara, Gujarat, 390002, India.
Singh R; Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, 390002, India. rajesh.singh-biochem@msubaroda.ac.in.

Apoptosis ; 27(11-12): 961-978, 2022 12.

Article en En | MEDLINE | ID: mdl-36018392

Asunto(s)

Neoplasias de la Mama Triple Negativas; Humanos; Apoptosis; Antígeno B7-H1; Daño del ADN/genética; Doxorrubicina/farmacología; Interleucina-6/genética; Interleucina-6/metabolismo; Proteínas de la Membrana/genética; Proteínas de la Membrana/metabolismo; Recurrencia Local de Neoplasia; FN-kappa B/genética; FN-kappa B/metabolismo; Nucleotidiltransferasas; Factor de Transcripción STAT3/genética; Factor de Transcripción STAT3/metabolismo; Neoplasias de la Mama Triple Negativas/tratamiento farmacológico; Neoplasias de la Mama Triple Negativas/genética; Microambiente Tumoral

Palabras clave

Drug resistance; IL-6; Immune escape; PD-L1; STAT3; STING

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de la Mama Triple Negativas Límite: Humans Idioma: En Revista: Apoptosis Año: 2022 Tipo del documento: Article País de afiliación: India

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