Macrophage derived miR-7219-3p-containing exosomes mediate fibroblast trans-differentiation by targeting SPRY1 in silicosis.

Niu, Zhiyuan; Wang, Lei; Qin, Xiaofeng; Ye, Zhimin; Xie, Bin; Hu, Yongbin

Niu, Zhiyuan; Wang, Lei; Qin, Xiaofeng; Ye, Zhimin; Xie, Bin; Hu, Yongbin.

Afiliación

Niu Z; Department of Pathology, School of Basic Medical Science, Central South University, Changsha 410013, PR China.
Wang L; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, PR China.
Qin X; Department of Pathology, School of Basic Medical Science, Central South University, Changsha 410013, PR China.
Ye Z; Department of Pathology, School of Basic Medical Science, Central South University, Changsha 410013, PR China.
Xie B; Department of Pathology, School of Basic Medical Science, Central South University, Changsha 410013, PR China.
Hu Y; Department of Pathology, School of Basic Medical Science, Central South University, Changsha 410013, PR China. Electronic address: yongbinhu@csu.edu.cn.

Toxicology ; 479: 153310, 2022 09.

Article en En | MEDLINE | ID: mdl-36075289

Asunto(s)

Exosomas; MicroARNs; Silicosis; Proteínas Adaptadoras Transductoras de Señales/metabolismo; Animales; Transdiferenciación Celular; Exosomas/genética; Fibroblastos/metabolismo; Macrófagos/metabolismo; Proteínas de la Membrana/metabolismo; Ratones; MicroARNs/genética; MicroARNs/metabolismo; Dióxido de Silicio/metabolismo; Dióxido de Silicio/toxicidad; Silicosis/genética

Palabras clave

Exosome; Fibroblast; Macrophage; MicroRNA; Silicosis

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Silicosis / MicroARNs / Exosomas Límite: Animals Idioma: En Revista: Toxicology Año: 2022 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google