Comparison of hydrophobicity scales for predicting biophysical properties of antibodies.

Waibl, Franz; Fernández-Quintero, Monica L; Wedl, Florian S; Kettenberger, Hubert; Georges, Guy; Liedl, Klaus R

Waibl, Franz; Fernández-Quintero, Monica L; Wedl, Florian S; Kettenberger, Hubert; Georges, Guy; Liedl, Klaus R.

Afiliación

Waibl F; Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria.
Fernández-Quintero ML; Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria.
Wedl FS; Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria.
Kettenberger H; Large Molecule Research, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Penzberg, Germany.
Georges G; Large Molecule Research, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Penzberg, Germany.
Liedl KR; Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria.

Front Mol Biosci ; 9: 960194, 2022.

Article en En | MEDLINE | ID: mdl-36120542

Palabras clave

antibodies; antibody structure; developability; developability prediction; hydrophobic interaction chromatography (HIC); hydrophobicity scale; hyrophobicity

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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Guideline / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Mol Biosci Año: 2022 Tipo del documento: Article País de afiliación: Austria

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