Trends in small molecule drug properties: A developability molecule assessment perspective.

Agarwal, Prashant; Huckle, James; Newman, Jake; Reid, Darren L

Agarwal, Prashant; Huckle, James; Newman, Jake; Reid, Darren L.

Afiliación

Agarwal P; Drug Product Technologies, Process Development, Amgen, One Amgen Center Drive, Thousand Oaks, CA 91320, USA. Electronic address: pagarw01@amgen.com.
Huckle J; Drug Product Technologies, Process Development, Amgen, One Amgen Center Drive, Thousand Oaks, CA 91320, USA.
Newman J; Drug Product Technologies, Process Development, Amgen, One Amgen Center Drive, Thousand Oaks, CA 91320, USA.
Reid DL; Drug Product Technologies, Process Development, Amgen, 360 Binney St, Cambridge, MA 02142, USA. Electronic address: dreid@amgen.com.

Drug Discov Today ; 27(12): 103366, 2022 12.

Article en En | MEDLINE | ID: mdl-36122862

Asunto(s)

Química Farmacéutica; Sistemas de Liberación de Medicamentos; Preparaciones Farmacéuticas/química; Solubilidad; Permeabilidad

Palabras clave

Developability molecule assessment; Drug delivery; Formulation; Physicochemical properties; Preformulation; Small molecules

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Química Farmacéutica / Sistemas de Liberación de Medicamentos Idioma: En Revista: Drug Discov Today Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2022 Tipo del documento: Article

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