The adenosine A (2A) receptor antagonist SCH58261 protects photoreceptors by inhibiting microglial activation and the inflammatory response.

Cheng, Yajia; Cao, Peipei; Geng, Chao; Chu, Xiaoqi; Li, Yuhao; Cui, Jianlin

Cheng, Yajia; Cao, Peipei; Geng, Chao; Chu, Xiaoqi; Li, Yuhao; Cui, Jianlin.

Afiliación

Cheng Y; Medical International Collaborative Innovation Center, Nankai University School of Medicine, Tianjin, China; Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, China.
Cao P; Medical International Collaborative Innovation Center, Nankai University School of Medicine, Tianjin, China.
Geng C; Medical International Collaborative Innovation Center, Nankai University School of Medicine, Tianjin, China.
Chu X; Medical International Collaborative Innovation Center, Nankai University School of Medicine, Tianjin, China.
Li Y; Beijing Geriatric Medical Research Center, Xuanwu Hospital, Capital Medical University, Beijing, China. Electronic address: liyuhao@xwhosp.org.
Cui J; Medical International Collaborative Innovation Center, Nankai University School of Medicine, Tianjin, China. Electronic address: cuijianlin@nankai.edu.cn.

Int Immunopharmacol ; 112: 109245, 2022 Nov.

Article en En | MEDLINE | ID: mdl-36150227

Asunto(s)

Microglía; Degeneración Retiniana; Animales; Humanos; Inflamación/tratamiento farmacológico; Degeneración Retiniana/tratamiento farmacológico; Pez Cebra; Receptor de Adenosina A2A

Palabras clave

Adenosine A (2A) receptor; Light damage; Microglia; Photoreceptor; SCH58261

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Degeneración Retiniana / Microglía Límite: Animals / Humans Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China

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