Aberrant Ganglioside Functions to Underpin Dysregulated Myelination, Insulin Signalling, and Cytokine Expression: Is There a Link and a Room for Therapy?

Svirin, Evgeniy; de Munter, Johannes; Umriukhin, Aleksei; Sheveleva, Elisaveta; Kalueff, Allan V; Svistunov, Andrei; Morozov, Sergey; Walitza, Susanne; Strekalova, Tatyana

Svirin, Evgeniy; de Munter, Johannes; Umriukhin, Aleksei; Sheveleva, Elisaveta; Kalueff, Allan V; Svistunov, Andrei; Morozov, Sergey; Walitza, Susanne; Strekalova, Tatyana.

Afiliación

Svirin E; Neuroplast BV, 6222 NK Maastricht, The Netherlands.
de Munter J; Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine and Department of Normal Physiology, Sechenov First Moscow State Medical University, 119048 Moscow, Russia.
Umriukhin A; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Sheveleva E; Neuroplast BV, 6222 NK Maastricht, The Netherlands.
Kalueff AV; Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine and Department of Normal Physiology, Sechenov First Moscow State Medical University, 119048 Moscow, Russia.
Svistunov A; Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine and Department of Normal Physiology, Sechenov First Moscow State Medical University, 119048 Moscow, Russia.
Morozov S; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Walitza S; Research Laboratory for Advanced Studies in Petrochemistry, Chemical Technology and Biotechnology, Ural Federal University, 620002 Yekaterinburg, Russia.
Strekalova T; Neuroscience Program, Sirius University of Science and Technology, 354340 Sochi, Russia.

Biomolecules ; 12(10)2022 10 07.

Article en En | MEDLINE | ID: mdl-36291644

Asunto(s)

Gangliósido G(M1); Gangliósidos; Animales; Ratones; Gangliósidos/metabolismo; Gangliósido G(M1)/metabolismo; Lactosilceramidos; Insulina; Citocinas; Estudio de Asociación del Genoma Completo; Receptor de Insulina; Mamíferos/metabolismo

Palabras clave

insulin receptor signalling; major brain gangliosides; mice; myelination; neurodevelopmental disorders; neuroinflammation

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Gangliósido G(M1) / Gangliósidos Límite: Animals Idioma: En Revista: Biomolecules Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos

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