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Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging.
Cabral-Miranda, Felipe; Tamburini, Giovanni; Martinez, Gabriela; Ardiles, Alvaro O; Medinas, Danilo B; Gerakis, Yannis; Hung, Mei-Li Diaz; Vidal, René; Fuentealba, Matias; Miedema, Tim; Duran-Aniotz, Claudia; Diaz, Javier; Ibaceta-Gonzalez, Cristobal; Sabusap, Carleen M; Bermedo-Garcia, Francisca; Mujica, Paula; Adamson, Stuart; Vitangcol, Kaitlyn; Huerta, Hernan; Zhang, Xu; Nakamura, Tomohiro; Sardi, Sergio Pablo; Lipton, Stuart A; Kennedy, Brian K; Henriquez, Juan Pablo; Cárdenas, J Cesar; Plate, Lars; Palacios, Adrian G; Hetz, Claudio.
Afiliación
  • Cabral-Miranda F; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
  • Tamburini G; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Martinez G; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Ardiles AO; Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
  • Medinas DB; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
  • Gerakis Y; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Hung MD; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Vidal R; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
  • Fuentealba M; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Miedema T; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Duran-Aniotz C; Centro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaiso, Valparaiso, Chile.
  • Diaz J; Centro de Neurología Traslacional, Escuela de Medicina, Universidad de Valparaíso, Valparaiso, Chile.
  • Ibaceta-Gonzalez C; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
  • Sabusap CM; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Bermedo-Garcia F; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Mujica P; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
  • Adamson S; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Vitangcol K; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Huerta H; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
  • Zhang X; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Nakamura T; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Sardi SP; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
  • Lipton SA; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Kennedy BK; Center for Integrative Biology, Universidad Mayor, Santiago, Chile.
  • Henriquez JP; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
  • Cárdenas JC; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Plate L; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Palacios AG; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
  • Hetz C; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.
EMBO J ; 41(22): e111952, 2022 11 17.
Article en En | MEDLINE | ID: mdl-36314651
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Encéfalo / Envejecimiento / Proteínas Serina-Treonina Quinasas / Respuesta de Proteína Desplegada / Proteína 1 de Unión a la X-Box Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: EMBO J Año: 2022 Tipo del documento: Article País de afiliación: Chile
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Encéfalo / Envejecimiento / Proteínas Serina-Treonina Quinasas / Respuesta de Proteína Desplegada / Proteína 1 de Unión a la X-Box Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: EMBO J Año: 2022 Tipo del documento: Article País de afiliación: Chile