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Poly(I:C) promotes neurotoxic amyloid ß accumulation through reduced degradation by decreasing neprilysin protein levels in astrocytes.
Yamamoto, Naoki; Tokumon, Takuya; Obuchi, Ayako; Kono, Mari; Saigo, Katsuyasu; Tanida, Mamoru; Ikeda-Matsuo, Yuri; Sobue, Kazuya.
Afiliación
  • Yamamoto N; Faculty of Pharmaceutical Sciences, Himeji Dokkyo University, Himeji, Hyogo, Japan.
  • Tokumon T; Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, Ishikawa, Japan.
  • Obuchi A; Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, Ishikawa, Japan.
  • Kono M; Faculty of Pharmaceutical Sciences, Himeji Dokkyo University, Himeji, Hyogo, Japan.
  • Saigo K; Scientific Research, Scientific Affairs, Sysmex Corporation, Kobe, Hyogo, Japan.
  • Tanida M; Faculty of Nursing, Himeji Dokkyo University, Himeji, Hyogo, Japan.
  • Ikeda-Matsuo Y; Department of Physiology II, Kanazawa Medical University, Uchinada, Ishikawa, Japan.
  • Sobue K; Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, Ishikawa, Japan.
J Neurochem ; 163(6): 517-530, 2022 12.
Article en En | MEDLINE | ID: mdl-36321194
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Virosis / Neprilisina / Astrocitos / Péptidos beta-Amiloides / Enfermedad de Alzheimer / Insulisina Límite: Animals Idioma: En Revista: J Neurochem Año: 2022 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Virosis / Neprilisina / Astrocitos / Péptidos beta-Amiloides / Enfermedad de Alzheimer / Insulisina Límite: Animals Idioma: En Revista: J Neurochem Año: 2022 Tipo del documento: Article País de afiliación: Japón