Neuropeptide FF indirectly affects testicular morphogenesis and functions in medaka.
Proc Natl Acad Sci U S A
; 119(46): e2209353119, 2022 11 16.
Article
en En
| MEDLINE
| ID: mdl-36343231
ABSTRACT
Testicular morphogenesis and functions are considered to be under the control of neural and endocrine systems. However, the available literature is mainly limited to mammals, and it remains unclear how they are regulated in teleost species. Here, we demonstrated that neuropeptide FF (NPFF) in the brain is responsible for the follicle-stimulating hormone expression in the pituitary, which facilitates the testicular morphogenesis and androgen synthesis, and subsequently contributes to successful spermatogenesis. The present findings give us important insights into the neuroendocrine regulatory mechanisms underlying the testicular morphogenesis and functions in teleosts.
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Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Oryzias
Límite:
Animals
Idioma:
En
Revista:
Proc Natl Acad Sci U S A
Año:
2022
Tipo del documento:
Article
País de afiliación:
Japón