Development of bicarbonate buffer flow-through cell dissolution test and its application in prediction of in vivo performance of colon targeting tablets.

Ikuta, Shotaro; Nakagawa, Hidetoshi; Kai, Toshiya; Sugano, Kiyohiko

Ikuta, Shotaro; Nakagawa, Hidetoshi; Kai, Toshiya; Sugano, Kiyohiko.

Afiliación

Ikuta S; Molecular Pharmaceutics Lab., College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1, Noji-higashi, Kusatsu, Shiga 525-8577, Japan; Pharmaceutical Research Laboratories, Pharmaceutical Department, Nipro corporation, 3023, Noji-Cho, Kusatsu, Shiga 525-0055, Japan. Electronic address: ikuta
Nakagawa H; Pharmaceutical Research Laboratories, Pharmaceutical Department, Nipro corporation, 3023, Noji-Cho, Kusatsu, Shiga 525-0055, Japan.
Kai T; Pharmaceutical Research Laboratories, Pharmaceutical Department, Nipro corporation, 3023, Noji-Cho, Kusatsu, Shiga 525-0055, Japan.
Sugano K; Molecular Pharmaceutics Lab., College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1, Noji-higashi, Kusatsu, Shiga 525-8577, Japan.

Eur J Pharm Sci ; 180: 106326, 2023 Jan 01.

Article en En | MEDLINE | ID: mdl-36347443

Asunto(s)

Bicarbonatos; Colon; Masculino; Humanos; Concentración de Iones de Hidrógeno; Comprimidos; Liberación de Fármacos; Solubilidad

Palabras clave

Bicarbonate; Bioequivalence; Colon targeting; Floating lid; Flow-through cell dissolution test

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Bicarbonatos / Colon Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans / Male Idioma: En Revista: Eur J Pharm Sci Asunto de la revista: FARMACIA / FARMACOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article

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