Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice.

Wang, Xiaojing; Huang, Shaowei; Zhang, Meiling; Su, Yulin; Pan, Zengfeng; Liang, Junjie; Xie, Xueqian; Wang, Qing; Chen, Jinyan; Zhou, Lian; Luo, Xia

Wang, Xiaojing; Huang, Shaowei; Zhang, Meiling; Su, Yulin; Pan, Zengfeng; Liang, Junjie; Xie, Xueqian; Wang, Qing; Chen, Jinyan; Zhou, Lian; Luo, Xia.

Afiliación

Wang X; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Huang S; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Zhang M; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Su Y; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Pan Z; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Liang J; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xie X; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Wang Q; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Chen J; Basic Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Zhou L; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China. Electronic address: zl@gzucm.edu.cn.
Luo X; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China. Electronic address: luoxia@gzucm.edu.cn.

J Ethnopharmacol ; 302(Pt B): 115919, 2023 Feb 10.

Article en En | MEDLINE | ID: mdl-36356716

Asunto(s)

Colitis Ulcerosa; Colitis; Microbioma Gastrointestinal; Ratones; Animales; Colitis Ulcerosa/inducido químicamente; Colitis Ulcerosa/tratamiento farmacológico; Colitis Ulcerosa/metabolismo; Sulfato de Dextran/toxicidad; Triptófano/metabolismo; Receptores de Hidrocarburo de Aril/metabolismo; Ratones Endogámicos C57BL; Colitis/tratamiento farmacológico; Colon; Proteínas de Uniones Estrechas/metabolismo; Indoles/farmacología; Modelos Animales de Enfermedad; Interleucina-22

Palabras clave

Aryl hydrocarbon receptor; Gegen Qinlian decoction; Gut microbiota; IL-22; Tryptophan metabolism; Ulcerative colitis

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Colitis / Microbioma Gastrointestinal Límite: Animals Idioma: En Revista: J Ethnopharmacol Año: 2023 Tipo del documento: Article País de afiliación: China

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