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Plaque contact and unimpaired Trem2 is required for the microglial response to amyloid pathology.
Wood, Jack I; Wong, Eugenia; Joghee, Ridwaan; Balbaa, Aya; Vitanova, Karina S; Stringer, Katie M; Vanshoiack, Alison; Phelan, Stefan-Laural J; Launchbury, Francesca; Desai, Sneha; Tripathi, Takshashila; Hanrieder, Jörg; Cummings, Damian M; Hardy, John; Edwards, Frances A.
Afiliación
  • Wood JI; Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, UK; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal Hospital, House V3, 43180 Mölnd
  • Wong E; Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, UK.
  • Joghee R; Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, UK.
  • Balbaa A; Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, UK.
  • Vitanova KS; Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, UK.
  • Stringer KM; Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, UK; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal Hospital, House V3, 43180 Mölnd
  • Vanshoiack A; Nanostring Technologies, 530 Fairview Avenue N, Seattle, WA 98109, United States.
  • Phelan SJ; Nanostring Technologies, 530 Fairview Avenue N, Seattle, WA 98109, United States.
  • Launchbury F; Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Desai S; Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, UK.
  • Tripathi T; Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, UK.
  • Hanrieder J; Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal Hospital, Hou
  • Cummings DM; Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, UK.
  • Hardy J; Dementia Research Institute, University College London, Gower Street, London WC1E 6BT, UK; Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Edwards FA; Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, UK; Institute of Healthy Ageing, University College London, Gower Street, London WC1E 6BT, UK. Electronic address: f.a.edwards@ucl.ac.uk.
Cell Rep ; 41(8): 111686, 2022 11 22.
Article en En | MEDLINE | ID: mdl-36417868
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Alzheimer / Amiloidosis Límite: Animals Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Alzheimer / Amiloidosis Límite: Animals Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article