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A novel 4'-brominated derivative of fisetin induces cell cycle arrest and apoptosis and inhibits EGFR/ERK1/2/STAT3 pathways in non-small-cell lung cancer without any adverse effects in mice.
Sabarwal, Akash; van Rooyen, Jaco C; Caburet, Jeremy; Avgenikos, Moscos; Dheeraj, Arpit; Ali, Mansoor; Mishra, Deepali; de Meester, Joséphine S B; Stander, Saskia; van Otterlo, Willem A L; Kaschula, Catherine H; Singh, Rana P.
Afiliación
  • Sabarwal A; Cancer Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
  • van Rooyen JC; Department of Chemistry and Polymer Science, Stellenbosch University, Matieland, South Africa.
  • Caburet J; Department of Chemistry and Polymer Science, Stellenbosch University, Matieland, South Africa.
  • Avgenikos M; Sigma Clermont, Université Clermont Auvergne, Aubière, France.
  • Dheeraj A; Department of Chemistry and Polymer Science, Stellenbosch University, Matieland, South Africa.
  • Ali M; Cancer Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
  • Mishra D; Cancer Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
  • de Meester JSB; Cancer Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
  • Stander S; Department of Chemistry and Polymer Science, Stellenbosch University, Matieland, South Africa.
  • van Otterlo WAL; Faculté des Sciences, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.
  • Kaschula CH; Department of Chemistry and Polymer Science, Stellenbosch University, Matieland, South Africa.
  • Singh RP; Department of Chemistry and Polymer Science, Stellenbosch University, Matieland, South Africa.
FASEB J ; 36(12): e22654, 2022 12.
Article en En | MEDLINE | ID: mdl-36421014

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: India

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: India