Need for speed: Key driver of host cell migration varies among mycobacteria.

Youngblom, Madison A; Pepperell, Caitlin S

Youngblom, Madison A; Pepperell, Caitlin S.

Afiliación

Youngblom MA; Microbiology Doctoral Training Program, University of Wisconsin-Madison, Madison, WI, USA; Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
Pepperell CS; Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA; Department of Medicine (Infectious Diseases), School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: cspepper@medicine.wisc.edu.

Cell ; 185(24): 4467-4469, 2022 11 23.

Article en En | MEDLINE | ID: mdl-36423577

RESUMEN

In this issue of Cell, Saelens et al. describe a new function for mycobacterial Type VII secretion systems: manipulation of host cell migration. They find that a substantial proportion of global TB cases arise from bacteria lacking this function, raising questions about its role in pathoadaptation of Mycobacterium tuberculosis.

Asunto(s)

Mycobacterium tuberculosis; Tuberculosis; Sistemas de Secreción Tipo VII; Humanos; Sistemas de Secreción Tipo VII/metabolismo; Mycobacterium tuberculosis/metabolismo; Tuberculosis/microbiología; Movimiento Celular

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Tuberculosis / Sistemas de Secreción Tipo VII / Mycobacterium tuberculosis Límite: Humans Idioma: En Revista: Cell Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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