Novel insights into atopic dermatitis.
J Allergy Clin Immunol
; 151(5): 1145-1154, 2023 05.
Article
en En
| MEDLINE
| ID: mdl-36428114
ABSTRACT
Recent research into the pathophysiology and treatment of atopic dermatitis (AD) has shown notable progress. An increasing number of aspects of the immune system are being implicated in AD, including the epithelial barrier, TH2 cytokines, and mast cells. Major advances in therapeutics were made in biologic cytokine and receptor antagonists and among Janus kinase inhibitors. We focus on these areas and address new insights into AD epidemiology, biomarkers, endotypes, prevention, and comorbidities. Going forward, we expect future mechanistic insights and therapeutic advances to broaden physicians' ability to diagnose and manage AD patients, and perhaps to find a cure for this chronic condition.
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Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Dermatitis Atópica
Límite:
Humans
Idioma:
En
Revista:
J Allergy Clin Immunol
Año:
2023
Tipo del documento:
Article