Three New Cembranoids from a Xisha Soft Coral Sarcophyton sp.
Chem Biodivers
; 20(1): e202200966, 2023 Jan.
Article
en En
| MEDLINE
| ID: mdl-36445809
ABSTRACT
Chemical investigation of the Xisha soft coral Sarcophyton sp. has led to the isolation of eight cembrane-type diterpenoids, including three new compounds, namely sarcophynoids A-C (1-3), and five known analog compounds (4-8). Their structures were clarified based on spectroscopic analysis, and computer-assisted methods including TDDFT-ECD calculation and the quantum mechanical-nuclear magnetic resonance (QM-NMR) method. All the above compounds were tested for their antibacterial activities. Among them, compounds 4-7 and 8 exhibited antibacterial activities against S. aureus, B. subtilis, and P. aeruginosa, with MIC of 4-64 µg/mL.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Antozoos
/
Diterpenos
Límite:
Animals
Idioma:
En
Revista:
Chem Biodivers
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2023
Tipo del documento:
Article
País de afiliación:
China