IGF2BP3 is an essential N<sup>6</sup>-methyladenosine biotarget for suppressing ferroptosis in lung adenocarcinoma cells.

Xu, Xin; Cui, Jiangtao; Wang, Hong; Ma, Lifang; Zhang, Xiao; Guo, Wanxin; Xue, Xiangfei; Wang, Yikun; Qiu, Shiyu; Tian, Xiaoting; Miao, Yayou; Wu, Mengyi; Yu, Yongchun; Xu, Yunhua; Wang, Jiayi; Qiao, Yongxia

IGF2BP3 is an essential N⁶-methyladenosine biotarget for suppressing ferroptosis in lung adenocarcinoma cells.

Xu, Xin; Cui, Jiangtao; Wang, Hong; Ma, Lifang; Zhang, Xiao; Guo, Wanxin; Xue, Xiangfei; Wang, Yikun; Qiu, Shiyu; Tian, Xiaoting; Miao, Yayou; Wu, Mengyi; Yu, Yongchun; Xu, Yunhua; Wang, Jiayi; Qiao, Yongxia.

Afiliación

Xu X; Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Cui J; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Wang H; Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Ma L; School of Public Health, Shanghai Jiao Tong University School of Medicine, 200025, China.
Zhang X; Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Guo W; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Xue X; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Wang Y; Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Qiu S; Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Tian X; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Miao Y; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Wu M; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Yu Y; Shanghai University of Traditional Chinese Medicine, 201203, China.
Xu Y; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.
Wang J; Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, PR China.
Qiao Y; Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.

Mater Today Bio ; 17: 100503, 2022 Dec 15.

Article en En | MEDLINE | ID: mdl-36457846

Palabras clave

ACSL3, acyl-CoA synthetase long chain family member 3; ALKBH5, alkB homolog 5; ELISA, enzyme-linked immunosorbent assay; FTH1, ferritin heavy chain 1; FTO, fat mass-and obesity-associated gene; Ferroptosis; GPX4, glutathione peroxidase 4; HNRNPA2B1, heterogeneous nuclear ribonucleoprotein A2/B1; IB, immunoblotting; IGF2BP3, insulin-like growth factor 2 mRNA binding protein 3; IHC, immunohistochemistry; LUAD, lung adenocarcinoma; Lung adenocarcinoma; MDA, malondialdehyde; METTL14, methyltransferase-like 14; METTL3, methyltransferase-like 3; PKM, pyruvate kinase M1/2; RBM15, RNA binding motif protein 15; ROS, reactive oxygen species; SLC3A2, solute carrier family 3 member 2; TMA, tissue microarray assay; Therapeutic target; VIRMA, vir-like m6A methyltransferase associated; WTAP, Wilms' tumor 1-associating protein; YTHDF2, YTH domain family 2; ZC3H13, zinc finger CCCH-type containing 13; m6A RNA methylation; m6A reader; m6A, N6-methyladenosine; qRT-PCR, quantitative reverse transcription PCR

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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Mater Today Bio Año: 2022 Tipo del documento: Article País de afiliación: China

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