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Verinurad does not prolong QTc interval: a thorough QT study using concentration-QTc modelling.
Parkinson, Joanna; Dota, Corina; Källgren, Christian; Gottfridsson, Christer; Bjursell, Magnus; Perl, Shira; KÓ§rnicke, Thomas; Rekic, Dinko; Johansson, Susanne.
Afiliación
  • Parkinson J; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences R&D, AstraZeneca, Gothenburg, Sweden.
  • Dota C; Cardiovascular Safety Center of Excellence and Safety Knowledge Group, Global Patient Safety, Oncology R&D, AstraZeneca, Gothenburg, Sweden.
  • Källgren C; Late-Stage Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Gottfridsson C; Cardiovascular Safety Center of Excellence and Safety Knowledge Group, Global Patient Safety, Oncology R&D, AstraZeneca, Gothenburg, Sweden.
  • Bjursell M; Late-Stage Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Perl S; Late-Stage Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA.
  • KÓ§rnicke T; Early Phase Clinical Unit, Parexel International, Berlin, Germany.
  • Rekic D; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences R&D, AstraZeneca, Gothenburg, Sweden.
  • Johansson S; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences R&D, AstraZeneca, Gothenburg, Sweden.
Br J Clin Pharmacol ; 89(6): 1747-1755, 2023 06.
Article en En | MEDLINE | ID: mdl-36504291
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Síndrome de QT Prolongado / Alopurinol Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Br J Clin Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: Suecia
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Síndrome de QT Prolongado / Alopurinol Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Br J Clin Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: Suecia