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KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.
Pan, Yuanwang; Han, Han; Hu, Hai; Wang, Hua; Song, Yueqiang; Hao, Yuan; Tong, Xinyuan; Patel, Ayushi S; Misirlioglu, Selim; Tang, Sittinon; Huang, Hsin-Yi; Geng, Ke; Chen, Ting; Karatza, Angeliki; Sherman, Fiona; Labbe, Kristen E; Yang, Fan; Chafitz, Alison; Peng, Chengwei; Guo, Chenchen; Moreira, Andre L; Velcheti, Vamsidhar; Lau, Sally C M; Sui, Pengfei; Chen, Haiquan; Diehl, J Alan; Rustgi, Anil K; Bass, Adam J; Poirier, John T; Zhang, Xiaoyang; Ji, Hongbin; Zhang, Hua; Wong, Kwok-Kin.
Afiliación
  • Pan Y; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Han H; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Hu H; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Wang H; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
  • Song Y; State Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Hao Y; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA; Applied Bioinformatics Laboratories, Office of Science and Research, New York University Grossman School of Medicine, New York, NY, USA.
  • Tong X; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
  • Patel AS; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Misirlioglu S; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Tang S; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Huang HY; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Geng K; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Chen T; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Karatza A; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Sherman F; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Labbe KE; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Yang F; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Chafitz A; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Peng C; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Guo C; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
  • Moreira AL; Department of Pathology, New York University School of Medicine, New York, NY, USA.
  • Velcheti V; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Lau SCM; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Sui P; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
  • Chen H; Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
  • Diehl JA; Department of Biochemistry, Case Western Reserve University and Case Comprehensive Cancer Center, Cleveland, OH, USA.
  • Rustgi AK; Herbert Irving Comprehensive Cancer Center, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
  • Bass AJ; Herbert Irving Comprehensive Cancer Center, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
  • Poirier JT; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
  • Zhang X; State Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Ji H; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China; School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou
  • Zhang H; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA; Hillman Cancer Center, UPMC, Pittsburgh, PA 15232, USA; Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: huz59@pitt.edu.
  • Wong KK; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA. Electronic address: kwok-kin.wong@nyulangone.org.
Cancer Cell ; 41(1): 88-105.e8, 2023 01 09.
Article en En | MEDLINE | ID: mdl-36525973

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Límite: Animals / Humans Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Límite: Animals / Humans Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos