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Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer.
Bell, Hannah N; Huber, Amanda K; Singhal, Rashi; Korimerla, Navyateja; Rebernick, Ryan J; Kumar, Roshan; El-Derany, Marwa O; Sajjakulnukit, Peter; Das, Nupur K; Kerk, Samuel A; Solanki, Sumeet; James, Jadyn G; Kim, Donghwan; Zhang, Li; Chen, Brandon; Mehra, Rohit; Frankel, Timothy L; Gyorffy, Balázs; Fearon, Eric R; Pasca di Magliano, Marina; Gonzalez, Frank J; Banerjee, Ruma; Wahl, Daniel R; Lyssiotis, Costas A; Green, Michael; Shah, Yatrik M.
Afiliación
  • Bell HN; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Huber AK; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
  • Singhal R; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Korimerla N; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA; University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
  • Rebernick RJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Kumar R; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA.
  • El-Derany MO; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biochemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
  • Sajjakulnukit P; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Das NK; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Kerk SA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Solanki S; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • James JG; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
  • Kim D; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Zhang L; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Chen B; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Mehra R; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Frankel TL; Department of Surgery, University of Michigan, Ann Arbor, MI, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
  • Gyorffy B; Department of Bioinformatics and 2(nd) Department of Pediatrics, Semmelweis University, Budapest, Hungary; TTK Cancer Biomarker Research Group, Institute of Enzymology, Budapest, Hungary.
  • Fearon ER; University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA; Department of Pathology, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Department of Human Genetics, University of Michigan, Ann Arbor, M
  • Pasca di Magliano M; Department of Surgery, University of Michigan, Ann Arbor, MI, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
  • Gonzalez FJ; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Banerjee R; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA.
  • Wahl DR; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA; University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
  • Lyssiotis CA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA; University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
  • Green M; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA; University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA; Veteran's Affairs Ann Arbor Healthcare System, Ann Arbor, MI, USA.
  • Shah YM; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA; University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. Electronic address: shahy@umich.e
Cell Metab ; 35(1): 134-149.e6, 2023 01 03.
Article en En | MEDLINE | ID: mdl-36528023
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Amoníaco Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Amoníaco Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos