Collagen VI expression is negatively mechanosensitive in pancreatic cancer cells and supports the metastatic niche.

Papalazarou, Vasileios; Drew, James; Juin, Amelie; Spence, Heather J; Whitelaw, Jamie; Nixon, Colin; Salmeron-Sanchez, Manuel; Machesky, Laura M

Papalazarou, Vasileios; Drew, James; Juin, Amelie; Spence, Heather J; Whitelaw, Jamie; Nixon, Colin; Salmeron-Sanchez, Manuel; Machesky, Laura M.

Afiliación

Papalazarou V; Cancer Research UK Beatson Institute, Switchback Road, Bearsden, Glasgow G61 1BD, UK.
Drew J; Centre for the Cellular Microenvironment, University of Glasgow,Glasgow G11 6EW, UK.
Juin A; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1BD, UK.
Spence HJ; Cancer Research UK Beatson Institute, Switchback Road, Bearsden, Glasgow G61 1BD, UK.
Whitelaw J; Cancer Research UK Beatson Institute, Switchback Road, Bearsden, Glasgow G61 1BD, UK.
Nixon C; Cancer Research UK Beatson Institute, Switchback Road, Bearsden, Glasgow G61 1BD, UK.
Salmeron-Sanchez M; Cancer Research UK Beatson Institute, Switchback Road, Bearsden, Glasgow G61 1BD, UK.
Machesky LM; Cancer Research UK Beatson Institute, Switchback Road, Bearsden, Glasgow G61 1BD, UK.

J Cell Sci ; 135(24)2022 12 15.

Article en En | MEDLINE | ID: mdl-36546396

Asunto(s)

Colágeno; Neoplasias Pancreáticas; Humanos; Colágeno/metabolismo; Matriz Extracelular/metabolismo; Neoplasias Pancreáticas/genética; Neoplasias Pancreáticas/patología; Integrinas/metabolismo; Microambiente Tumoral; Neoplasias Pancreáticas

Palabras clave

Cancer metastasis; Collagen VI; Extracellular matrix; Integrin adhesion; Mechanosensing; Pancreatic cancer

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Colágeno Límite: Humans Idioma: En Revista: J Cell Sci Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

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