A novel strategy for designing the magic shotguns for distantly related target pairs.

Luo, Yongchao; Wang, Panpan; Mou, Minjie; Zheng, Hanqi; Hong, Jiajun; Tao, Lin; Zhu, Feng

Luo, Yongchao; Wang, Panpan; Mou, Minjie; Zheng, Hanqi; Hong, Jiajun; Tao, Lin; Zhu, Feng.

Afiliación

Luo Y; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Wang P; College of Chemistry and Pharmaceutical Engineering, Huanghuai University, Zhumadian 463000, China.
Mou M; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Zheng H; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Hong J; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Tao L; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicine of Zhejiang Province, School of Medicine, Hangzhou Normal University, Hangzhou 310036, China.
Zhu F; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

Brief Bioinform ; 24(1)2023 01 19.

Article en En | MEDLINE | ID: mdl-36631399

Asunto(s)

Descubrimiento de Drogas; Polifarmacología; Descubrimiento de Drogas/métodos; Ensayos Analíticos de Alto Rendimiento

Palabras clave

dual inhibitor; enrichment factor; false discovery rate; polypharmacology; quantitative structureactivity relationship (QSAR); virtual screening

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Descubrimiento de Drogas / Polifarmacología Tipo de estudio: Prognostic_studies Idioma: En Revista: Brief Bioinform Asunto de la revista: BIOLOGIA / INFORMATICA MEDICA Año: 2023 Tipo del documento: Article País de afiliación: China

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